William Mondy

William Mondy

Institution/Organization: University of South Florida

Department: Pharmaceutical Sciences

Academic Status: Faculty

Biography:

I am an experienced and ambitious Associate/Assistant Professor and scientific researcher with over 20 years of experience in both capacities. My teaching and research interests are multidisciplinary, spanning biomedical imaging, tissue engineering, biomechanics, regenerative medicine, and others throughout my career. This is demonstrated by my expansive work and education history and my current teaching and research, which is now focused on reverse engineering of 3-D tissue using computer-aided designed (CAD) tissue scaffolding to support cell and tissue regeneration to replace necrotic, cancerous tissue, or otherwise dysfunctional tissue or organs. Early in my scientific work, I established a firm foundational understanding of the structures and functions of human organs at a cellular ultrastructural level. I began my research career at the Armed Forces Institute of Pathology, studying the ultrastructure anatomy of human tissues under the tutorage of world-renowned pathologists. I am currently researching and teaching bio-fabrication of composite tissues for transplantation therapy. My current work is being conducted through the National I-Corps TEAMS through NSF, where I lead the research team as the principal investigator and Technical Lead. This project explicitly addresses using the novel neural regenerative scaffold process I developed to guide a blastema-based regenerative process for wound healing.

Motivation:

In my work, I acquired high-resolution image data that needs to be accurately reconstructed into the authentic architecture of tissues and organs on a microscopic level. In addition, I cold into 3D models created by this image data Hash table is used to signal peripheral devices in a coordinated manufacturing process used to produce functional tissues for human transplant therapy. Coordinated with this manufacturing process, I provide Cartesian coordinates assigned to said 3D models on the micron scale, if required, to instruct femtosecond laser and 3D bioprinting techniques robotically. Robotically control processes are performed in sequence with procedures described in the Hash table explicitly created for a given tissue typing; examples in long cardiac tissue, skin, bones, etc.